COMPLEMENT FACTOR-H AND RELATED PROTEINS - AN EXPANDING FAMILY OF COMPLEMENT-REGULATORY PROTEINS

被引：134

作者：

ZIPFEL, PF

SKERKA, C

机构：

来源：

IMMUNOLOGY TODAY | 1994年 / 15卷 / 03期

关键词：

D O I：

10.1016/0167-5699(94)90155-4

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Recently, several factor-H-related molecules have been identified in humans and mice, initiating new interest in this group of serum proteins. Although no complement-regulatory activity has been demonstrated yet for the human factor-H-related proteins, the immunological and structural similarities to factor H suggest overlapping functions. Here, Peter Zipfel and Christine Skerka review these similarities and suggest a new nomenclature to identify members of the factor-H-related family.

引用

收藏

页码：121 / 126

页数：6

相关论文

共 34 条

[1] LOCALIZATION OF THE COMPLEMENT-COMPONENT-C3B-BINDING SITE AND THE COFACTOR ACTIVITY FOR FACTOR-I IN THE 38KDA TRYPTIC FRAGMENT OF FACTOR-H [J].

ALSENZ, J ;

LAMBRIS, JD ;

SCHULZ, TF ;

DIERICH, MP .

BIOCHEMICAL JOURNAL, 1984, 224 (02) :389-398

[2] STRUCTURAL AND FUNCTIONAL-ANALYSIS OF THE COMPLEMENT COMPONENT FACTOR-H WITH THE USE OF DIFFERENT ENZYMES AND MONOCLONAL-ANTIBODIES TO FACTOR-H [J].

ALSENZ, J ;

SCHULZ, TF ;

LAMBRIS, JD ;

SIM, RB ;

DIERICH, MP .

BIOCHEMICAL JOURNAL, 1985, 232 (03) :841-850

[3] SOLUTION STRUCTURE OF THE 5TH REPEAT OF FACTOR-H - A 2ND EXAMPLE OF THE COMPLEMENT CONTROL PROTEIN MODULE [J].

BARLOW, PN ;

NORMAN, DG ;

STEINKASSERER, A ;

HORNE, TJ ;

PEARCE, J ;

DRISCOLL, PC ;

SIM, RB ;

CAMPBELL, ID .

BIOCHEMISTRY, 1992, 31 (14) :3626-3634

[4] SOLUTION STRUCTURE OF A PAIR OF COMPLEMENT MODULES BY NUCLEAR-MAGNETIC-RESONANCE [J].

BARLOW, PN ;

STEINKASSERER, A ;

NORMAN, DG ;

KIEFFER, B ;

WILES, AP ;

SIM, RB ;

CAMPBELL, ID .

JOURNAL OF MOLECULAR BIOLOGY, 1993, 232 (01) :268-284

[5] SECONDARY STRUCTURE OF A COMPLEMENT CONTROL PROTEIN MODULE BY 2-DIMENSIONAL H-1-NMR [J].

BARLOW, PN ;

BARON, M ;

NORMAN, DG ;

DAY, AJ ;

WILLIS, AC ;

SIM, RB ;

CAMPBELL, ID .

BIOCHEMISTRY, 1991, 30 (04) :997-1004

[6] HUMAN GENES FOR 3 COMPLEMENT COMPONENTS THAT REGULATE THE ACTIVATION OF C-3 ARE TIGHTLY LINKED [J].

DECORDOBA, SR ;

LUBLIN, DM ;

RUBINSTEIN, P ;

ATKINSON, JP .

JOURNAL OF EXPERIMENTAL MEDICINE, 1985, 161 (05) :1189-1195

[7]

DISCIPIO RG, 1992, J IMMUNOL, V149, P2592

[8]

ESTALLER C, 1991, J IMMUNOL, V146, P3190

[9] EVOLUTION OF THE COMPLEMENT-SYSTEM [J].

FARRIES, TC ;

ATKINSON, JP .

IMMUNOLOGY TODAY, 1991, 12 (09) :295-300

[10] POLYMORPHISM AND DEFICIENCY OF HUMAN FACTOR H-RELATED PROTEIN-P39 AND PROTEIN-P37 [J].

FEIFEL, E ;

PRODINGER, WM ;

MOLGG, M ;

SCHWAEBLE, W ;

SCHONITZER, D ;

KOISTINEN, V ;

MISASI, R ;

DIERICH, MP .

IMMUNOGENETICS, 1992, 36 (02) :104-109

← 1 2 3 4 →