PREVENTION OF DRUG-INDUCED NEPHROTOXICITY IN THE INTENSIVE-CARE UNIT

被引：41

作者：

HOCK, R ^{[1
]}

ANDERSON, RJ ^{[1
]}

机构：

[1] VET ADM MED CTR,MED SERV 111,DENVER,CO 80220

来源：

JOURNAL OF CRITICAL CARE | 1995年 / 10卷 / 01期

关键词：

D O I：

10.1016/0883-9441(95)90029-2

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Acute renal failure (ARF) occurs in 5% to 25% of all admissions to an intensive care unit (ICU).(65) Th, development of ICU-associated ARF increases the average mortality from about 15% to more than 60%.(65) ARF is also associated with significant prolongation of hospital stay as well as substantial expense. Recent studies suggest that a significant percent of hospital acquired ARF is caused by nephrotoxins.(12,29,63) This brief review will discuss the frequency of occurrence, pathophysiology, risk factors, clinical course, and prevention of nephrotoxicity that may occur after exposure to aminoglycosides, nonsteroidal anti-inflammatory drugs, and radiographic contrast agents. Copyright (C) 1995 by W.B. Saunders Company

引用

页码：33 / 43

页数：11

共 75 条

[1]

Aitken, Burns, McArdle, Et al., Effects of ketorolac trometamol on renal function, Br J Anaesth, 68, pp. 481-485, (1992)

[2]

Anderson, Schrier, Acute tubular necrosis, Diseases of the Kidney, pp. 1287-1318, (1993)

[3]

Anderson, Berl, McDonald, Et al., Prostaglandins: Effects on blood pressure renal blood flow, sodium and water excretion, Kidney Int, 10, pp. 205-215, (1976)

[4]

Appel, Aminoglycoside nephrotoxicity, The American Journal of Medicine, 88, (1990)

[5]

Appel, Given, Levin, Et al., Vancomycin and the kidney, Am J Kid Dis, 8, pp. 75-80, (1986)

[6]

Barrett, Carlisle, Metaanalysis of the relative nephrotoxicity of high- and low-osmolality contrast media, Radiology, 188, pp. 171-178, (1993)

[7]

Barrett, Contrast nephrotoxicity, J Am Soc Nephrol, 5, pp. 125-137, (1994)

[8]

Berns, Nephrotoxicity of contrast media, Kidney Int, 36, pp. 730-740, (1989)

[9]

Bertino, Booker, Franck, Et al., Incidence of and significant risk factors for aminoglycoside-associated nephrotoxicity in patients dosed by using individualized pharmacokinetic monitoring, J Inf Dis, 167, pp. 173-179, (1993)

[10]

Blackshear, Davidman, Stillason, Identification of risk for renal insufficiency from NSAIDS, Arch Int Med, 143, pp. 1130-1134, (1983)

← 1 2 3 4 5 6 7 8 →