RISK-FACTORS FOR RENAL-CELL CARCINOMA IN DENMARK .1. ROLE OF SOCIOECONOMIC-STATUS, TOBACCO USE, BEVERAGES, AND FAMILY HISTORY

被引：74

作者：

MELLEMGAARD, A

ENGHOLM, G

MCLAUGHLIN, JK

OLSEN, JH

机构：

[1] Division for Cancer Epidemiology, Danish Cancer Society, Copenhagen, DK-2100

[2] Division of Cancer Etiology, Biostatistics Branch, National Cancer Institute, Bethesda, Maryland

来源：

CANCER CAUSES & CONTROL | 1994年 / 5卷 / 02期

关键词：

ALCOHOL; COFFEE; DENMARK; FAMILY HISTORY; RENAL CELL CARCINOMA; SOCIOECONOMIC STATUS; TEA; TOBACCO;

D O I：

10.1007/BF01830256

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Risk factors for renal cell carcinoma were examined in a population based case-control study in Denmark. A total of 368 cases and 396 age- and gender-matched controls were interviewed in their homes. Increased risk was associated with low socioeconomic status. For men, an increasing risk with decreasing socioeconomic status was seen (odds ratio [OR] = 2.2, 95 percent confidence interval [CI] = 1.0-4.6 for men in the lowest socioeconomic stratum cf the highest). For women, the risk was lower in the highest socioeconomic stratum compared with the rest (OR = 2.4, CI = 0.9-5.9 for the lowest strata If the highest). Cigarette smoking was a risk factor in men with an OR = 2.3 (CI = 1.1-5.1) for cigarette smokers with a total consumption of more than 40 pack-years compared with nonsmokers. Family history of kidney cancer was associated with an increased risk in both genders (for men, OR = 4.1, CI = 1.1-14.9; for women, OR = 4.8, CI = 1.0-23). Observations were inconsistent regarding coffee and alcohol consumption, and we found no association with tea drinking. The association with socioeconomic status remained after adjustment for other factors.

引用

页码：105 / 113

页数：9

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