ANTIDEPRESSANT DRUG-THERAPY IN THE ELDERLY - A CRITICAL-REVIEW OF THE CONTROLLED CLINICAL-TRIALS CONDUCTED SINCE 1980

被引:34
作者
VOLZ, HP
MOLLER, HJ
机构
[1] Psychiatrische Abteilung, Universitat Bonn, D-53105 Bonn
关键词
D O I
10.1055/s-2007-1014286
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
We report on the results of controlled clinical antidepressant trials with elderly depressed patients which meet certain methodological requirements and have been published since 1980. The safety, tolerability, and efficacy of the investigated compounds are reviewed. In the light of the diagnostic problems and the altered pharmacokinetic behavior in this special age group we conclude that the progress in scientific knowledge in the last 13 years has only been moderate.
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页码:93 / 100
页数:8
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