MOLECULAR-CONFORMATIONS OF MET-ENKEPHALIN - COMPARISON OF ZWITTERIONIC AND CATIONIC FORMS

被引:49
作者
JONES, CR
GARSKY, V
GIBBONS, WA
机构
[1] UNIV WISCONSIN, COLL AGR & LIFE SCI, DEPT BIOCHEM, MADISON, WI 53706 USA
[2] UNIV WISCONSIN, COLL AGR & LIFE SCI, INST ENZYME, MADISON, WI 53706 USA
[3] WYETH LABS INC, RADNOR, PA 19087 USA
关键词
D O I
10.1016/0006-291X(77)91546-7
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Apparent discrepancies in published assignments of the PMR spectrum of Met5-enkephalin were due to the existence of 2 forms, cationic and zwitterionic. The PMR parameters of these 2 forms indicated different secondary conformations. The PMR parameters of the zwitterionic form were indicative of a 2-5 .beta.-I turn but no secondary conformation could be suggested for the cationic form with the present data.
引用
收藏
页码:619 / 625
页数:7
相关论文
共 12 条