SIMULATED MOVING-BED CHROMATOGRAPHY FOR CONTINUOUS SEPARATION OF 2 COMPONENTS AND ITS APPLICATION TO BIOREACTORS

被引：18

作者：

ADACHI, S

机构：

[1] Department of Food Science and Technology, Faculty of Agriculture, Kyoto University, Sakyo-ku, Kyoto

来源：

JOURNAL OF CHROMATOGRAPHY A | 1994年 / 658卷 / 02期

关键词：

D O I：

10.1016/0021-9673(94)80020-0

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Simulated moving-bed chromatography (SMBC) is a powerful technique to separate continuously two components in large amounts, and is useful on a preparative scale. Models for the calculation of the concentration profiles in SMBC are introduced, and also methods for design of the chromatograph and for the determination of operating conditions. Improved chromatographs developed to separate three components are described. The combination of chromatographic separation and an enzyme-catalysed reaction to improve the reaction performance is also described.

引用

页码：271 / 282

页数：12

共 42 条

[1] AN ENZYME REACTOR BASED ON THE DIFFERENCE IN MIGRATION RATE IN GEL CHROMATOGRAPHIC COLUMNS BETWEEN ENZYME AND SUBSTRATE [J].