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DIASPIRIN CROSS-LINKED HEMOGLOBIN (DCLHB(TM)) POLYMERIZATION
被引：12
作者：
HAI, TT
NELSON, D
PEREIRA, D
SRNAK, A
机构：
[1] Blood Substitutes Program, Baxter Healthcare Corporation, Round Lake,Illonois
来源：
ARTIFICIAL CELLS BLOOD SUBSTITUTES AND IMMOBILIZATION BIOTECHNOLOGY
|
1994年
/
22卷
/
03期
关键词：
D O I：
10.3109/10731199409117931
中图分类号：
Q81 [生物工程学（生物技术）];
Q93 [微生物学];
学科分类号：
071005 ;
0836 ;
090102 ;
100705 ;
摘要：
By employing proprietary polymerization agents possessing specific binding groups and by completing diaspirin crosslinked hemoglobin (DCLHb) polymerization under specific conditions, we have selectively achieved the following objectives: (1) the P-50 was adjusted to the physiologic range or left- or right-shifted; (2) the surface of DCLHb was modified (''decorated''); (3) DCLHb was polymerized but not decorated; (4) DCLHb was polymerized and decorated; or (5) DCLHb was site-specifically modified and polymerized.
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页码：923 / 931
页数：9
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