EVOLUTION OF GENETIC APPARATUS

被引：695

作者：

ORGEL, LE

机构：

[1] The Salk Institute for Biological Studies San Diego

来源：

JOURNAL OF MOLECULAR BIOLOGY | 1968年 / 38卷 / 03期

关键词：

D O I：

10.1016/0022-2836(68)90393-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

It is argued that the evolution of the genetic apparatus must have required the abiotic formation of macromolecules capable of residue-by-residue replication. This suggests that polynucleotides were present even in the most primitive ancestors of contemporary organisms. Models which explain the evolution of the association between polynucleotide and polypeptide sequences are discussed. © 1968.

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页码：381 / &

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