A REINVESTIGATION OF DEMETHYLATION OF MYCOPHENOLIC ACID

被引：7

作者：

SEDEN, TP

TURNER, RW

TURNER, WB

机构：

[1] Pharmaceuticals Division, I.C.I. Ltd., Macclesfield, Cheshire, Alderley Park

来源：

TETRAHEDRON | 1969年 / 25卷 / 19期

关键词：

D O I：

10.1016/S0040-4020(01)83032-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reaction of mycophenolic acid (I, R = Me, R1 = H) with hydriodic acid has been shown to give the isomeric chromans (II and III) and the lactone IV. Chroman II was previously thought to be desmethylmycophenolic acid (I, R, R1 = H). With hydriodic acid both chromans, (II and III) give a similar equilibrium mixture. © 1969.

引用

页码：4915 / &

共 4 条

[1] STUDIES IN THE BIOCHEMISTRY OF MICRO-ORGANISMS .78. THE MOLECULAR CONSTITUTION OF MYCOPHENOLIC ACID, A METABOLIC PRODUCT OF PENICILLIUM BREVI-COMPACTUM DIERCKX .2. POSSIBLE STRUCTURAL FORMULAE FOR MYCOPHENOLIC ACID [J].