ENDOGENOUS SUPEROXIDE-DISMUTASE ACTIVITY IN 2 BABESIA SPECIES

被引：16

作者：

BECUWE, P

SLOMIANNY, C

VALENTIN, A

SCHREVEL, J

CAMUS, D

DIVE, D

机构：

[1] INSERM,U42,DOMAINE CERTIA,369 RUE JULES GUESDE,BP 39,F-59651 VILLENEUVE DASCQ,FRANCE

[2] CNRS,URA 290,BIOL CELLULAIRE LAB,F-86022 POITIERS,FRANCE

[3] MUSEUM NATL HIST NAT,BIOL PARASITAIRE & CHIMIOTHERAPIE LAB,F-75231 PARIS 05,FRANCE

来源：

PARASITOLOGY | 1992年 / 105卷

关键词：

BABESIA; SUPEROXIDE DISMUTASE; IRON;

D O I：

10.1017/S0031182000074084

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Babesia hylomysci and B. divergens were studied for superoxide dismutase (SOD) activity by enzyme assay and isoelectric focusing (IEF). In the two Babesia species, parasite-associated SOD is cyanide-insensitive and inhibited by H2O2, indicating that iron is the cofactor metal. Measurements of SOD activity from purified parasites show that the SOD activity detected in Babesia is, for the main part, due to an endogenous enzyme.

引用

页码：177 / 182

页数：6

共 27 条

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