SYNTHESIS OF LIN-BENZOALLOPURINOL

被引：16

作者：

FOSTER, RH ^{[1
]}

LEONARD, NJ ^{[1
]}

机构：

[1] UNIV ILLINOIS,ROGER ADAMS LAB,SCH CHEM SCI,URBANA,IL 61801

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1979年 / 44卷 / 25期

关键词：

D O I：

10.1021/jo00393a032

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of pyrazolo [4, 3-g]quinazolin-5-one (tin-benzoallopurinol, 1), a fluorescent analogue of 4- hydroxypyrazolo[3, 4-d]pyrimidine (allopurinol), by a route commencing with a trisubstituted benzene is described. The title compound was found to be a substrate for but not an inhibitor of xanthine oxidase. © 1979, American Chemical Society. All rights reserved.

引用

页码：4609 / 4611

页数：3

共 30 条

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