A NEW VECTOR USING THE HUMAN MULTIDRUG RESISTANCE GENE AS A SELECTABLE MARKER ENABLES OVEREXPRESSION OF FOREIGN GENES IN EUKARYOTIC CELLS

被引：51

作者：

KANE, SE ^{[1
]}

REINHARD, DH ^{[1
]}

FORDIS, CM ^{[1
]}

PASTAN, I ^{[1
]}

GOTTESMAN, MM ^{[1
]}

机构：

[1] NCI, MOLEC BIOL LAB, BLDG 37, RM 2E18, BETHESDA, MD 20892 USA

来源：

GENE | 1989年 / 84卷 / 02期

关键词：

D O I：

10.1016/0378-1119(89)90518-0

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

引用

页码：439 / 446

页数：8

共 26 条

[1] FILM DETECTION METHOD FOR TRITIUM-LABELED PROTEINS AND NUCLEIC-ACIDS IN POLYACRYLAMIDE GELS [J].

BONNER, WM ;

LASKEY, RA .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1974, 46 (01) :83-88

[2] VECTORS FOR EXPRESSION AND AMPLIFICATION OF CDNA IN MAMMALIAN-CELLS - EXPRESSION OF RAT PHENYLALANINE-HYDROXYLASE [J].

CHOO, KH ;

FILBY, RG ;

JENNINGS, IG ;

PETERSON, G ;

FOWLER, K .

DNA-A JOURNAL OF MOLECULAR & CELLULAR BIOLOGY, 1986, 5 (06) :529-537

[3] DHFR COAMPLIFICATION OF T-PA IN DHFR+ BOVINE ENDOTHELIAL-CELLS - INVITRO CHARACTERIZATION OF THE PURIFIED SERINE PROTEASE [J].

CONNORS, RW ;

SWEET, RW ;

NOVERAL, JP ;

PFARR, DS ;

TRILL, JJ ;

SHEBUSKI, RJ ;

BERKOWITZ, BA ;

WILLIAMS, D ;

FRANKLIN, S ;

REFF, ME .

DNA-A JOURNAL OF MOLECULAR & CELLULAR BIOLOGY, 1988, 7 (09) :651-661

[4] AMPLIFICATION OF DNA-SEQUENCES IN HUMAN MULTIDRUG-RESISTANT KB CARCINOMA-CELLS [J].

FOJO, AT ;

WHANGPENG, J ;

GOTTESMAN, MM ;

PASTAN, I .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1985, 82 (22) :7661-7665

[5] PROCESSING AND LYSOSOMAL LOCALIZATION OF A GLYCOPROTEIN WHOSE SECRETION IS TRANSFORMATION STIMULATED [J].

GAL, S ;

WILLINGHAM, MC ;

GOTTESMAN, MM .

JOURNAL OF CELL BIOLOGY, 1985, 100 (02) :535-544

[6]

GERMANN UA, 1989, J BIOL CHEM, V264, P7418

[7] RECOMBINANT GENOMES WHICH EXPRESS CHLORAMPHENICOL ACETYLTRANSFERASE IN MAMMALIAN-CELLS [J].

GORMAN, CM ;

MOFFAT, LF ;

HOWARD, BH .

MOLECULAR AND CELLULAR BIOLOGY, 1982, 2 (09) :1044-1051

[8]

GOTTESMAN MM, 1988, J BIOL CHEM, V263, P12163

[9] STABLE EXPRESSION OF CDNA-ENCODING THE HUMAN INTERLEUKIN-2 RECEPTOR IN EUKARYOTIC CELLS [J].

GREENE, WC ;

ROBB, RJ ;

SVETLIK, PB ;

RUSK, CM ;

DEPPER, JM ;

LEONARD, WJ .

JOURNAL OF EXPERIMENTAL MEDICINE, 1985, 162 (01) :363-368

[10]

HOLTER W, 1987, J IMMUNOL, V138, P2917

← 1 2 3 →