CEFOTAXIME-INDUCED IMMUNE HEMOLYTIC-ANEMIA DUE TO ANTIBODIES REACTING INVITRO BY MORE THAN ONE MECHANISM

被引：23

作者：

SHULMAN, IA

ARNDT, PA

MCGEHEE, W

GARRATTY, G

机构：

[1] UNIV SO CALIF,LOS ANGELES CTY MED CTR,TRANSFUS MED UNIT,LOS ANGELES,CA 90033

[2] UNIV SO CALIF,LOS ANGELES CTY MED CTR,DEPT HEMATOL,LOS ANGELES,CA 90033

来源：

TRANSFUSION | 1990年 / 30卷 / 03期

关键词：

D O I：

10.1046/j.1537-2995.1990.30390194351.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Until recently, all cephalosporin‐induced immune hemolytic anemias appeared to react by a “penicillin‐type” drug adsorption mechanism, and hemolysis was extra‐vascular. In 1987 and 1988, the first two cases of cephalosporin‐induced immune hemolytic anemia with intravascular hemolysis associated with a so‐called immune complex mechanism were reported. This report describes a case of extravascular hemolysis due to a third‐generation cephalosporin, cefotaxime, which, to the authors' knowledge, is the first to show in vitro characteristics of both the drug adsorption and the so‐called immune complex mechanisms. 1990 AABB

引用

页码：263 / 266

页数：4

共 24 条

[1] EXTRAVASCULAR HEMOLYSIS FOLLOWING THE ADMINISTRATION OF CEFAMANDOLE [J].