FINE-NEEDLE ASPIRATION OF FIBROADENOMAS OF THE BREAST WITH ATYPIA - A SPECTRUM INCLUDING CASES THAT CYTOLOGICALLY MIMIC CARCINOMA

被引：42

作者：

STANLEY, MW

TANI, EM

SKOOG, L

机构：

[1] Department of Pathology, Hennepin County Medical Center, Minneapolis, Minnesota

[2] The Division of Clinical Cytology, The Institute of Tumor Pathology, Karolinska Hospital, Stockholm

来源：

DIAGNOSTIC CYTOPATHOLOGY | 1990年 / 6卷 / 06期

关键词：

BREAST; FIBROADENOMA; CARCINOMA; CYTOLOGY; FINE-NEEDLE ASPIRATION;

D O I：

10.1002/dc.2840060602

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

We herein report the cytologic and histologic findings in 11 cases of cytologically atypical fibroadenoma (FA). These ranged from cases recognizable as FA but showing epithelial atypia to cases that, even on review, completely mimicked the needle aspiration picture of ductal breast carcinoma. A retrospective review of 45 cases of previously excised FA showed that focal atypia is common (27%). Possible physiologic explanations for atypia in FA, along with strategies for avoiding false diagnoses of malignancy in aspiration smears, are discussed.

引用

页码：375 / 382

页数：8

共 11 条

[1]

Koss LG, Woyke S, Olszewski W, Aspiration biopsy: cytologic interpretation and histologic bases, pp. 67-69, (1984)

[2]

Linsk J, Kreuzer G, Zajicek J, Cytologic diagnosis of mammary tumors from aspiration biopsy smears: II, Studies on 210 fibroadenomas and 210 cases of benign dysplasia. Acta Cytol, 16, pp. 130-138, (1972)

[3]

Zajicek J, Aspiration biopsy cytology. Part 1. Cytology of supradiaphragmatic organs, (1974)

[4]

Svane G, Silfersward C, Stereotoxic needle biopsy of nonpalpable breast lesions: cytologic and histologic findings, Acta Radiol Diagn, 24, pp. 283-288, (1983)

[5]

Pike AM, Oberman HA, Juvenile (cellular) fibroadenoma: a clinicopathologic study, Am J Surg Pathol, 9, pp. 730-736, (1985)

[6]

Stanley MW, Tani EM, Rutquist LE, Skoog L, Cystosarcoma phyllodes of the breast: a cytologic and clinicopathologic study of 23 cases, Diagn Cytopathol, 5, pp. 29-34, (1989)

[7]

Silva JS, Georgiade GS, Dilley WG, McCarty KS, Wells SA, Menstrual cycle‐dependent variations of breast cyst fluid protein and sex steroid receptors in the normal human breast, Cancer, 51, pp. 1297-1302, (1983)

[8]

Longacre TA, Bartow SA, A correlative morphologic study of human breast and endometrium in the menstrual cycle, Am J Surg Pathol, 10, pp. 382-393, (1986)

[9]

Bottles K, Chan JS, Holly FA, Chiu S-H, Miller TR, Cytologic criteria for fibroadenoma: a step‐wise logistic regression analysis, Am J Clin Pathol, 89, pp. 707-713, (1988)

[10]

Fondo EY, Rosen PP, Fracchia AA, Urban JA, The problem of carcinoma developing in a fibroadenoma: recent experience at Memorial Hospital, Cancer, 43, pp. 563-567, (1979)

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