GENETIC-ENGINEERING OF HYBRID ANTIBIOTICS - A PROGRESS REPORT

被引：9

作者：

FLOSS, HG ^{[1
]}

STROHL, WR ^{[1
]}

机构：

[1] OHIO STATE UNIV,DEPT MICROBIOL,COLUMBUS,OH 43210

来源：

TETRAHEDRON | 1991年 / 47卷 / 31期

基金：

美国国家科学基金会; 美国国家卫生研究院;

关键词：

D O I：

10.1016/S0040-4020(01)86495-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Interspecies cloning of antibiotic biosynthesis genes in streptomycetes can be used to generate new hybrid natural product structures; the application of this approach to polyketide and its extension to thiopeptide antibiotics are summarized.

引用

页码：6045 / 6058

页数：14

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