ORGANIC-REACTIONS CATALYZED BY SOLID SUPERACIDS .5. PERFLUORINATED SULFONIC-ACID RESIN (NAFION-H) CATALYZED INTRAMOLECULAR FRIEDEL-CRAFTS ACYLATION

被引：62

作者：

YAMATO, T

HIDESHIMA, C

PRAKASH, GKS

OLAH, GA

机构：

[1] UNIV SO CALIF, DONALD P & KATHERINE B LOKER HYDROCARBON RES INST, LOS ANGELES, CA 90089 USA

[2] UNIV SO CALIF, DEPT CHEM, LOS ANGELES, CA 90089 USA

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1991年 / 56卷 / 12期

关键词：

D O I：

10.1021/jo00012a033

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Nafion-H, a perfluorinated sulfonic acid resin, catalyzed the intramolecular Friedel-Crafts acylation of diarylalkane-2-carboxylic acids and arylalkanoic acids in refluxing p-xylene to provide cyclic ketones. The reactions were clean, and the water that was formed as a byproduct did not deactivate the catalyst. It was also found that the intramolecular acylation of the corresponding acid chlorides occurred under much milder reaction conditions. The mechanism of the reaction is discussed.

引用

页码：3955 / 3957

页数：3

共 15 条

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