TREATMENT RESISTANCE OF DEPRESSION AFTER HEAD-INJURY - A PRELIMINARY-STUDY OF AMITRIPTYLINE RESPONSE

被引：60

作者：

DINAN, TG ^{[1
]}

MOBAYED, M ^{[1
]}

机构：

[1] UNIV DUBLIN TRINITY COLL, SCH MED, DEPT PSYCHIAT, DUBLIN 2, IRELAND

来源：

ACTA PSYCHIATRICA SCANDINAVICA | 1992年 / 85卷 / 04期

关键词：

AFFECTIVE DISORDER; ANTIDEPRESSANT DRUG; AMITRIPTYLINE; HEAD INJURY;

D O I：

10.1111/j.1600-0447.1992.tb01472.x

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Thirteen patients with depression following minor head injury were matched with 13 functional depressives. Both groups were indistinguishable psychopathologically. Five of the functional group had a family history of affective disorder and none of the head-injury group had such a history. Both groups were treated with amitriptyline, beginning with 100 mg daily, increasing to a maximum of 250 mg/d. There were significant differences in response between the 2 groups, with only 4 of the head-injury patients improving. Our preliminary results suggest that this condition is relatively resistant to tricyclic therapy.

引用

页码：292 / 294

页数：3

共 16 条

[11]

MONTGOMERY A, 1984, LANCET, V1, P1011

[12]

NOSEWORTHY F, 1983, INJURY, V14, P111

[13] BRAIN-STEM AUDITORY EVOKED-POTENTIALS IN POST-CONCUSSION DIZZINESS [J].

ROWE, MJ ;

CARLSON, C .

ARCHIVES OF NEUROLOGY, 1980, 37 (11) :679-683

[14]

SARAN AS, 1985, J CLIN PSYCHIAT, V46, P335

[15] ANXIETY AND DEPRESSION AFTER MILD HEAD-INJURY - A CASE CONTROL STUDY [J].

SCHOENHUBER, R ;

GENTILINI, M .

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1988, 51 (05) :722-724

[16]

*STAT GRAPH CORP, 1987, STATGR

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