PERSISTENT CATHETER-RELATED BACTEREMIA - CLEARANCE WITH ANTIBIOTICS AND UROKINASE

被引:28
作者
ASCHER, DP
SHOUPE, BA
MAYBEE, D
FISCHER, GW
机构
[1] UNIFORMED SERV UNIV HLTH SCI,DEPT PEDIAT INFECT DIS,BETHESDA,MD 20814
[2] WALTER REED ARMY MED CTR,DEPT PEDIAT HEMATOL ONCOL,WASHINGTON,DC 20307
关键词
CENTRAL VENOUS CATHETER-RELATED BACTEREMIA; UROKINASE;
D O I
10.1016/0022-3468(93)90675-B
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
A patient with terminal osteogenic sarcoma and catheterrelated coagulase-negative staphylococcal bacteremia was treated with vancomycin and blood cultures were positive for 4 days documented with quantitative colony counts. Urokinase therapy was initiated and was associated with a transient bacteremia with markedly increased colony counts of coagulase-negative Staphylococcus prior to eradication of the catheter-related infection. We feel that the combination of urokinase and appropriate antibiotics may be an effective method to eradicate line-associated coagulase-negative staphylococcal infection in selected patients. © 1993.
引用
收藏
页码:627 / 629
页数:3
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