STATISTICAL-MECHANICS OF SUPERCOILS AND THE TORSIONAL STIFFNESS OF THE DNA DOUBLE HELIX

被引:115
作者
VOLOGODSKII, AV
ANSHELEVICH, VV
LUKASHIN, AV
FRANKKAMENETSKII, MD
机构
[1] Institute of Molecular Genetics, Academy of Sciences of the USSR
关键词
D O I
10.1038/280294a0
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
The distribution of closed unknotted polymer chains over the writhing number is calculated by the Monte-Carlo method. For circular duplex DNA the variance of the distribution equals approximately half the observed variance of equilibrium distribution over the linking number. The balance which arises from fluctuations in DNA twisting makes it possible to estimate the torsional stiffness of the double helix. © 1979 Nature Publishing Group.
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页码:294 / 298
页数:5
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