BK VIRUS-DNA - CLEAVAGE MAP AND SEQUENCE-ANALYSIS

被引：27

作者：

YANG, RCA ^{[1
]}

WU, R ^{[1
]}

机构：

[1] CORNELL UNIV,DEPT BIOCHEM MOLEC & CELL BIOL,ITHACA,NY 14853

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1978年 / 75卷 / 05期

关键词：

D O I：

10.1073/pnas.75.5.2150

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

A detailed physical map of the BK virus (MM strain) genome has been constructed with respect to the cleavage sites of 11 different restriction enzymes. The enzymes cut BKV(MM) DNA at 61 specific sites whose locations have been determined. Preliminary nucleotide sequence was carried out in the region from 0.70 - 0.75 map positions on BKV(MM) DNA. An 80% homology was found at 0.714 - 0.744 map positions on BKV(MM) DNA with 0.722 - 0.752 map positions on simian virus 40 DNA. This region of simian virus 40 DNA codes for the synthesis of the leader sequence of late mRNA.

引用

页码：2150 / 2154

页数：5

共 27 条

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