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CHOLERETIC AND CHOLESTATIC EFFECTS OF INFUSED BILE-SALTS IN THE RAT

被引：51
作者：
DREW, R
PRIESTLY, BG
机构：
[1] Department of Human Physiology and Pharmacology, The University of Adelaide, Adelaide, 5001, South Australia
来源：
EXPERIENTIA | 1979年 / 35卷 / 06期
关键词：
D O I：
10.1007/BF01968265
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
In rats, at low infusion rates taurocholate (TC), taurochenodeoxycholate (TCDC) and taurodeoxycholate (TCD) each produced an increase in bile flow of 20-50%. However, at high infusion rates (5-20 μmoles min-1 kg-1) the cholestatic effects of the bile salts were revealed and the relative toxicity of the bile salts was seen to be TDC>TCDC>TC. © 1979 Birkhäuser Verlag.
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页码：809 / 811
页数：3
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