GRADING LIPOSARCOMAS WITH PET USING [F-18] FDG

被引：62

作者：

ADLER, LP

BLAIR, HF

WILLIAMS, RP

PATHRIA, MN

MAKLEY, JT

JOYCE, MJ

ALKAISI, N

MIRALDI, F

机构：

[1] UNIV HOSP CLEVELAND,DEPT PATHOL,CLEVELAND,OH 44106

[2] UNIV HOSP CLEVELAND,DEPT ORTHOPED,CLEVELAND,OH 44106

来源：

JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY | 1990年 / 14卷 / 06期

关键词：

Cancer staging; Emission computed tomography; Liposarcoma; Radioisotopes;

D O I：

10.1097/00004728-199011000-00017

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Five patients with liposarcomas of the thigh were studied using positron emission tomography (PET) with [18F]2-deoxy-2-fluoroglucose (FDG). There were three low-grade tumors (all National Cancer Institute Grade 1 myxoid liposarcomas) and two high-grade tumors (both pleomorphic liposarcomas, Grades 2 and 3). The low-grade liposarcomas were easily identified with an average dose uptake ratio (DUR) of 1.38 ± 0.045 (mean ± SD). The high-grade lesions were more avid for FDG with a mean DUR of 2.45 ± 0.24. There was a significant difference (p = 0.004) in the DUR for the two groups and the histological grade of malignancy was highly correlated with the DUR for FDG (Rho = 0.89). These findings suggest that FDG-PET may be useful for distinguishing between low-grade and high-grade liposarcomas. © 1990 Raven Press, Ltd., New York.

引用

页码：960 / 962

页数：3

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