HOW THE MESSENGER GOT ITS TAIL - ADDITION OF POLY(A) IN THE NUCLEUS

被引：392

作者：

WICKENS, M

机构：

[1] Department of Biochemistry, The Graduate School, College of Agriculture and Life Sciences, Madison

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1990年 / 15卷 / 07期

关键词：

D O I：

10.1016/0968-0004(90)90054-F

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Most mRNAs end in a poly(A) tail, the addition of which is catalysed by a poly(A) polymerase in conjunction with a distinct factor that provides specificity for mRNAs. The reaction is dynamic, involving separable initiation, elongation and termination phases. A companion article in next month's TIBS will review the regulation of poly(A) addition and removal during early animal development. © 1990.

引用

页码：277 / 281

页数：5

共 33 条

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