X-LINKED CHARCOT-MARIE-TOOTH DISEASE - A LINKAGE STUDY IN A LARGE FAMILY BY USING 12 PROBES OF THE PERICENTROMERIC REGION

被引：36

作者：

MOSTACCIUOLO, ML

MULLER, E

FARDIN, P

MICAGLIO, GF

BARDONI, B

GUIOLI, S

CAMERINO, G

DANIELI, GA

机构：

[1] UNIV PADUA,DIPARTMENTO BIOL,VIA TRIESTE 75,I-35100 PADUA,ITALY

[2] UNIV PAVIA,I-27100 PAVIA,ITALY

[3] UNIV PADUA,NEUROL CLIN,I-35100 PADUA,ITALY

来源：

HUMAN GENETICS | 1991年 / 87卷 / 01期

关键词：

D O I：

10.1007/BF01213086

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Linkage analysis was performed on 41 subjects belonging to a large family with a recurrence of X-linked Charcot-Marie-Tooth disease (CMTX), by using 12 restriction fragment length polymorphism markers mapping in p11-q13. The results are in agreement with previous linkage data. Three new markers that are potentially useful for genetic analysis of CMTX families are described. A more precise estimate of the localization of the disease locus was attempted by multipoint linkage analysis.

引用

页码：23 / 27

页数：5

共 14 条

[1]

ARVEILER B, 1987, Genomics, V1, P60, DOI 10.1016/0888-7543(87)90105-4

[2] LOCALIZATION OF X-LINKED DOMINANT CHARCOT-MARIE-TOOTH DISEASE (CMT 2) TO XQ13 [J].