PATELLAMIDE-E - A NEW CYCLIC PEPTIDE FROM THE ASCIDIAN LISSOCLINUM-PATELLA

被引：63

作者：

MCDONALD, LA ^{[1
]}

IRELAND, CM ^{[1
]}

机构：

[1] UNIV UTAH,DEPT MED CHEM,SALT LAKE CITY,UT 84112

来源：

JOURNAL OF NATURAL PRODUCTS | 1992年 / 55卷 / 03期

关键词：

D O I：

10.1021/np50081a016

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

A new cyclic peptide, patellamide E [1], was isolated from the ascidian Lissoclinum patella collected at Pulau Salu, Singapore. Its structure was determined by nmr spectroscopy, and its absolute configuration by acid hydrolysis and analysis of the derivatized constituent amino acids by hplc. Patellamide E was mildly cytotoxic against human colon tumor cells in vitro.

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页码：376 / 379

页数：4

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