DOT-ELISA FOR DETECTION OF PHENOLIC GLYCOLIPID PGL-TB1 AND DIACYL-TREHALOSE ANTIGENS OF MYCOBACTERIUM-TUBERCULOSIS

被引：14

作者：

PAPA, F

LUQUIN, M

DAVID, HL

机构：

[1] INST PASTEUR,UNITE TB & MYCOBACTERIES,F-75724 PARIS 15,FRANCE

[2] UNIV AUTONOMA BARCELONA,HOSP SANTA CRUZ & SAN PABLO,DEPT MICROBIOL,E-08025 BARCELONA,SPAIN

来源：

RESEARCH IN MICROBIOLOGY | 1992年 / 143卷 / 03期

关键词：

GLYCOLIPID; MYCOBACTERIUM TUBERCULOSIS; DAT; PGL-TB1; DOT-ELISA; DETECTION;

D O I：

10.1016/0923-2508(92)90024-I

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A DOT-ELISA method for detection of 2,3-diacyl-trehalose (DAT, previously referred to as SL-IV antigen) and triglycosyl phenol phthiocerol di-mycocerosate (PGL-Tbl) antigens from Mycobacterium tuberculosis is described. The method enabled the detection of both antigens in 14 clinical isolates of M. tuberculosis from different geographic origins; the presence of the glycolipids was confirmed by chemical analysis. It was therefore concluded that the synthesis of both of these compounds is characteristic of the species.

引用

页码：327 / 331

页数：5

共 17 条

[1] USE OF THE SL-IV AND THE PGL-TB1 GLYCOLIPID ANTIGENS IN ELISA FOR THE DIAGNOSIS OF TUBERCULOSIS IN AIDS PATIENTS [J].