A VARIANT MESSENGER-RNA SPECIES ENCODING A TRUNCATED FORM OF FAS ANTIGEN IN THE RAT-LIVER

被引：41

作者：

KIMURA, K ^{[1
]}

WAKATSUKI, T ^{[1
]}

YAMAMOTO, M ^{[1
]}

机构：

[1] NATL DEF MED COLL,DEPT BIOCHEM,TOKOROZAWA,SAITAMA 359,JAPAN

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1994年 / 198卷 / 02期

关键词：

D O I：

10.1006/bbrc.1994.1097

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A variant form of the Fas antigen cDNA was isolated from the rat liver. The cDNA contains an insertion sequence of 25 nuecleotide residues and codes for a protein consisting of 65 amino acids representing a signal peptide and an N-terminal portion of the extracytoplasmic domain of Fas antigen. The expression of a variant mRNA species is less abundant in the liver compared with that of an ordinary mRNA species. The variant mRNA, though its function is unknown, is plausibly produced by an alternative splicing. © 1994 Academic Press, Inc.

引用

页码：666 / 674

页数：9

共 26 条

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