AUTOMATED-METHOD FOR ANALYSIS OF NICOTINIC-ACID IN SERUM

被引：7

作者：

ROBINSON, WT ^{[1
]}

COSYNS, L ^{[1
]}

KRAML, M ^{[1
]}

机构：

[1] AYERST RES LABS,DEPT BIOCHEM,POB 6115,MONTREAL H3C 3J1,QUEBEC,CANADA

来源：

CLINICAL BIOCHEMISTRY | 1978年 / 11卷 / 02期

关键词：

D O I：

10.1016/S0009-9120(78)90667-7

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

Rational antihyperlipemic therapy, based on the use of nicotinic acid and its derivatives and/or combinations demands a rapid and reliable method for monitoring nicotinic acid blood levels. To this end, an automated colorimetric method for the analysis of nicotinic acid in serum has been elaborated. For serum from rats, dogs and man given p.o. nicotinic acid or 3-pyridine methanol, the method is > 90% specific for nicotinic acid. The limit detection for nicotinic acid is 2 μg/ml based on 0.15 ml of serum, or 0.3 μg/ml based on 1.5 ml of serum. © 1978.

引用

页码：46 / 49

页数：4

共 14 条

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