ACTH SENSITIVE ADENYL CYCLASE IN BOVINE ADRENAL CORTEX MEMBRANE FRACTIONS

被引：23

作者：

HECHTER, O

BAR, HP

MATSUBA, M

SOIFER, D

机构：

[1] Institute for Biomedical Research American Medical Association-Education, Research Foundation Chicago

来源：

LIFE SCIENCES PART 1 PHYSIOLOGY AND PHARMACOLOGY AND PART 2 BIOCHEMISTRY GENERAL AND MOLECULAR BIOLOGY | 1969年 / 8卷 / 17P1期

关键词：

D O I：

10.1016/0024-3205(69)90422-6

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Adenyl cyclase in bovine adrenal cortex was distributed in all particulate fractions obtained by differential centrifugation; factors in the 105,000 g supernate markedly inhibited cyclase activity. A major fraction of the total enzyme is associated with mitochondria. In all membranous fractions, the enzyme was stimulated by NaF and ACTH, but not by MSH, thyrotropin, glucagon or vasopressin; epinephrine variably stimulated cyclase to a small extent relative to ACTH. © 1969.

引用

页码：935 / &

共 9 条

[1] BAR HP, IN PRESS
[2] GRAHAMESMITH DG, 1967, CLIN RES, V15, P259
[3] HECHTER O, 1964, HORMONES, V5, P687
[4] IDENTITY OF SITE OF ACTION OF 3' 5'-ADENOSINE MONOPHOSPHATE AND ADRENOCORTOCOTROPIC HORMONE IN CORTICOSTEROIDOGENESIS IN RAT ADRENAL AND BEEF ADRENAL CORTEX SLICES
KARABOYAS, GC
KORITZ, SB
[J]. BIOCHEMISTRY, 1965, 4 (03) : 462 - +
[5] EVIDENCE FOR INCREASED DNA TEMPLATE ACTIVITY IN REGENERATING LIVER NUCLEI
POGO, AO
ALLFREY, VG
MIRSKY, AE
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1966, 56 (02) : 550 - +
[6] SOME ASPECTS OF BIOLOGICAL ROLE OF ADENOSINE 3',5'-MONOPHOSPHATE (CYCLIC AMP)
SUTHERLAND, EW
ROBISON, GA
BUTCHER, RW
[J]. CIRCULATION, 1968, 37 (02) : 279 - +
[7] TAUNTON OD, 1967, J CLIN INVEST, V46, P1122
[8] ACTH STIMULATION OF ADENYL CYCLASE IN ADRENAL HOMOGENATES
TAUNTON, OD
ROTH, J
PASTAN, I
[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1967, 29 (01) : 1 - &
[9] TAUNTON OD, 1969, J BIOL CHEM, V244, P247

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