CIRCADIAN VARIATION OF THE STREPTOZOTOCIN-DIABETOGENIC EFFECT IN MICE

被引:25
作者
CANDELA, S
HERNANDEZ, RE
GAGLIARDINO, JJ
机构
[1] Facultad de Ciencias Médicas, Centro de Endocrinología Experimental y Aplicada (UNLP-CONICET), La Plata, 1900
来源
EXPERIENTIA | 1979年 / 35卷 / 09期
关键词
D O I
10.1007/BF01963323
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Streptozotocin was injected in normal mice every 4h, during the day. Greatest number of diabetic animals were obtained at 16.00 h (95%) and lowest at 08.00 h (50%). Magnitude of hyperglycemia also showed similar distribution. This effect might be considered when planning its use for both experimental and clinical purposes. © 1979 Birkhäuser Verlag.
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页码:1256 / 1257
页数:2
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