ISOPROTERENOL IN COMPARISON TO WR-2721 AS A CHEMORADIOPROTECTOR OF THE RAT PAROTID-GLAND

被引:16
作者
SODICOFF, M
CONGER, AD
PRATT, NE
机构
[1] Temple University School of Medicine, Department of Anatomy, Philadelphia, PA
关键词
Amino-thiols; Chemoradioprotector; Isoproterenol; Phosphorothioates; Rat salivary gland; Wr-2721; X-irradiation;
D O I
10.1097/00004424-197903000-00010
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
A comparison was made of the radioprotective abilities of the chemoradioprotector WR-2721, an amino-thioi, and the β-sympathomimetic secretogogue isoproterenol on the rat parotid gland. Using the dose-response curve of WR-2721 for gland weights as a basis for comparison, isoproterenol was found to offer significant and equal protection during both the acute (DMF, 2.5) and the chronic (DMF, 2.3) periods. © J. B. Lippincott Company.
引用
收藏
页码:166 / 170
页数:5
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