PSEUDOSEMIGLABRIN, A PLATELET-AGGREGATION INHIBITOR FROM TEPHROSIA-SEMIGLABRA

被引：19

作者：

JONATHAN, LT

GBEASSOR, M

CHE, CT

FONG, HHS

FARNSWORTH, NR

LEBRETON, GC

VENTON, DL

机构：

[1] UNIV ILLINOIS,COLL PHARM,PROGRAM COLLABORAT RES PHARMACEUT SCI,CHICAGO,IL 60680

[2] UNIV ILLINOIS,COLL MED,DEPT PHARM,CHICAGO,IL 60680

[3] UNIV ILLINOIS,COLL PHARM,DEPT MED CHEM & PHARMACOGNOSY,CHICAGO,IL 60680

来源：

JOURNAL OF NATURAL PRODUCTS | 1990年 / 53卷 / 06期

关键词：

D O I：

10.1021/np50072a029

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Following bioassay-directed fractionation procedures, two 7-oxygenated-8-prenylflavones, (-)-psedosemiglabrin [1] and (-)-semiglabrin [2], were isolated from an MeOH extract of Tephrosia semiglabra. (-)-Pseudosemiglabrin [1] displayed in vitro inhibitory effects on human platelet aggregation.

引用

页码：1572 / 1574

页数：3

共 16 条

[1] NATURAL OCCURRENCE OF TEPHROSIA FLAVONES
AHMAD, S
[J]. PHYTOCHEMISTRY, 1986, 25 (04) : 955 - 958
[2] MAJOR FLAVONOIDS OF TEPHROSIA-NUBICA
AMMAR, NM
JARVIS, BB
[J]. JOURNAL OF NATURAL PRODUCTS, 1986, 49 (04): : 719 - 720
[3] INHIBITION OF AGGREGATION AND SECRETION OF HUMAN-PLATELETS BY QUERCETIN AND OTHER FLAVONOIDS - STRUCTURE ACTIVITY RELATIONSHIPS
BERETZ, A
CAZENAVE, JP
ANTON, R
[J]. AGENTS AND ACTIONS, 1982, 12 (03): : 382 - 387
[4] AGGREGATION OF BLOOD PLATELETS BY ADENOSINE DIPHOSPHATE AND ITS REVERSAL
BORN, GVR
[J]. NATURE, 1962, 194 (4832) : 927 - &
[5] POTENTIAL ANTIMALARIAL CANDIDATES FROM AFRICAN PLANTS - AN INVITRO APPROACH USING PLASMODIUM-FALCIPARUM
KHALID, SA
FAROUK, A
GEARY, TG
JENSEN, JB
[J]. JOURNAL OF ETHNOPHARMACOLOGY, 1986, 15 (02) : 201 - 209
[6] MODIFICATION OF PLATELET-FUNCTION AND ARACHIDONIC-ACID METABOLISM BY BIOFLAVONOIDS - STRUCTURE ACTIVITY RELATIONS
LANDOLFI, R
MOWER, RL
STEINER, M
[J]. BIOCHEMICAL PHARMACOLOGY, 1984, 33 (09) : 1525 - 1530
[7] MAHMOUD ZF, 1981, SCI PHARM, V49, P184
[8] SEPARATION OF DITERPENOID ALKALOID MIXTURES USING VACUUM LIQUID-CHROMATOGRAPHY
PELLETIER, SW
CHOKSHI, HP
DESAI, HK
[J]. JOURNAL OF NATURAL PRODUCTS, 1986, 49 (05): : 892 - 900
[9] 8-SUBSTITUTED FLAVONOIDS AND 3'-SUBSTITUTED 7-OXYGENATED CHALCONES FROM TEPHROSIA-PURPUREA
PELTER, A
WARD, RS
RAO, EV
RAJU, NR
[J]. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1981, (09): : 2491 - 2498
[10] 2 FLAVONOIDS FROM TEPHROSIA-PURPUREA
RAO, EV
RAJU, NR
[J]. PHYTOCHEMISTRY, 1984, 23 (10) : 2339 - 2342

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