INVIVO AND INVITRO EFFECTS OF ALLOXAN ON COLLAGEN CHARACTERISTICS OF BONE, SKIN AND TENDON OF SWISS MICE

被引：15

作者：

BEHERA, HN ^{[1
]}

PATNAIK, BK ^{[1
]}

机构：

[1] BERHAMPUR UNIV,POST GRAD DEPT ZOOL,BERHAMPUR 760007,ORISSA,INDIA

来源：

GERONTOLOGY | 1979年 / 25卷 / 05期

关键词：

Alloxan diabetes; Collagen; Mouse tissues;

D O I：

10.1159/000212350

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

Alloxan diabetes in Swiss mice induced decreased levels of percent solubility of collagen in bone, skin and tendon both after 4 days (96 h) and 28 days of treatment. In vitro treatment of tissues with alloxan in physiological saline did not influence the cross-linking of collagen. It is suggested that in alloxan diabetes, metabolites formed in the tissues might accelerate aging of collagen. © 1979 S. Karger AG, Basel.

引用

页码：255 / 260

页数：6

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