(E)-ALPHA-HYDROXY AND (Z)-ALPHA-HYDROXY AND ALPHA-METHOXYIMINO-4-NITRO-1H-IMIDAZOLE-1-ACETIC ACIDS AND ESTERS - SPECTRAL PROPERTIES, CONFORMATIONS AND PHOTOISOMERIZATION OF THE NEW COMPOUNDS

被引：4

作者：

ELITROPI, G

PANTO, E

TRICERRI, S

机构：

[1] Pierrel S.P.A. Research Laboratories, Milan, 20159

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1979年 / 16卷 / 08期

关键词：

D O I：

10.1002/jhet.5570160805

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Detailed experimental procedures are given for the preparation of the stereoisomeric (E)‐ and (Z)‐methyl‐α‐hydroxy and α‐methoxyimino‐4‐nitro‐1H‐imidazole‐1‐acetates and of the related acids. (Z)‐Isomers have been prepared by synthesis. (E)‐Isomers have been obtained only by photoisomerization. Decarboxylation of the acids left the corresponding aldehydes which are ideal compounds for structural studies and configurational assignments. Copyright © 1979 Journal of Heterocyclic Chemistry

引用

页码：1545 / 1550

页数：6

共 14 条

[1] BERNHART C, 1976, EUR J MED CHEM, V11, P369
[2] 2-AMINO-4-THIAZOLYL ACETIC-ACID DERIVATIVES OF CEPHALOSPORINS - EFFECT OF PRESENCE AND CONFIGURATION OF AN OXYIMINO GROUP ON ANTIBACTERIAL ACTIVITY
BUCOURT, R
HEYMES, R
LUTZ, A
PENASSE, L
PERRONNET, J
[J]. TETRAHEDRON, 1978, 34 (14) : 2233 - 2243
[3] ALKYLATION OF SYN- AND ANTI-BENZALDOXIMES
BUEHLER, E
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1967, 32 (02) : 261 - &
[4] COSAR C, 1966, ARZNEI-FORSCHUNG, V16, P23
[5] CARBON-NITROGEN ROTATIONAL BARRIER AS A STEREOCHEMICAL PROBE OF BENZAMIDOXIMES
DONDONI, A
LUNAZZI, L
GIORGIANNI, P
MACCIANTELLI, D
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1975, 40 (20) : 2979 - 2980
[6] STEREOCHEMISTRY OF HYDROXIMIC ACID-DERIVATIVES - CRYSTAL AND MOLECULAR-STRUCTURE OF N-PHENYL-2,6-DICHLOROBENZAMIDE OXIME
DONDONI, A
GILLI, G
SACERDOTI, M
[J]. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2, 1976, (09): : 1036 - 1040
[7] ELGUERO J, 1974, B SOC CHIM FR I-PHYS, P1137
[8] AMIDOXIMES - DETERMINATION OF CONFIGURATION AND STUDY OF Z-E ISOMERIZATION MECHANISM
GOZLAN, H
MICHELOT, R
RICHE, C
RIPS, R
[J]. TETRAHEDRON, 1977, 33 (19) : 2535 - 2542
[9] GOZLAN H, 1975, TETRAHEDRON LETT, P859
[10] GUILLOTEDELHEIT G, 1977, B SOC CHIM FR II-CH, P368

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