STIMULATING EFFECT OF ANGIOTENSIN-II ON THE SPONTANEOUS RELEASE OF NEWLY SYNTHETIZED [DOPAMINE-H-3 IN RAT STRIATAL SLICES

被引：57

作者：

SIMONNET, G ^{[1
]}

GIORGUIEFFCHESSELET, MF ^{[1
]}

机构：

[1] COLL FRANCE,INSERM,U114,GRP NB,F-75231 PARIS 5,FRANCE

来源：

NEUROSCIENCE LETTERS | 1979年 / 15卷 / 2-3期

关键词：

D O I：

10.1016/0304-3940(79)96105-6

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Angiotensin II (A II) (10-6 M, 10-5 M, 5 · 10-5 M) stimulated the spontaneous release of [3H]dopamine (DA) continuously synthetized from [3H]tyrosine in striatal slices of the rat. The A II-evoked release of [3H]-DA was prevented when slices were superfused with a calcium-free medium containing EGTA 5 · 10-4 M. It was also suppressed in the presence of the potent antagonist Sar1-Ile3-angiotensin. © 1979.

引用

页码：153 / 158

页数：6

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