AN EFFICIENT, LARGE-SCALE SYNTHESIS OF IDOXIFENE ((E)-1-[4-[2-(N-PYRROLIDINO)ETHOXY]PHENYL]-1-(4-IODOPHENYL)-2-PHENYL-1-BUTENE)

被引：2

作者：

MCCAGUE, R ^{[1
]}

POTTER, GA ^{[1
]}

JARMAN, M ^{[1
]}

机构：

[1] INST CANC RES,CANC RES CAMPAIGN LAB,DRUG DEV SECT,15 COTSWOLD RD,SUTTON SM2 5NG,SURREY,ENGLAND

来源：

ORGANIC PREPARATIONS AND PROCEDURES INTERNATIONAL | 1994年 / 26卷 / 03期

关键词：

D O I：

10.1080/00304949409458432

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[No abstract available]

引用

页码：343 / 346

页数：4

共 8 条

[1]

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[2] COMPLEXATION AS A FACTOR IN METALATION REACTIONS - METALATION OF 1-METHOXY-2-PHENOXYETHANE [J].

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[3]

HAYNES B P, 1991, Breast Cancer Research and Treatment, V19, P174

[4] DERIVATIVES OF TAMOXIFEN - DEPENDENCE OF ANTIESTROGENICITY ON THE 4-SUBSTITUENT [J].

MCCAGUE, R ;

LECLERCQ, G ;

LEGROS, N ;

GOODMAN, J ;

BLACKBURN, GM ;

JARMAN, M ;

FOSTER, AB .

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[5]

MCCAGUE R, 1986, J CHEM RES-S, P58

[6]

MCCAGUE R, 1986, Patent No. 8621908

[7]

MCCAGUE R, 1986, J CHEM RES M, P771

[8] VARIATION OF THE INHIBITION OF CALMODULIN DEPENDENT CYCLIC-AMP PHOSPHODIESTERASE AMONGST ANALOGS OF TAMOXIFEN - CORRELATIONS WITH CYTOTOXICITY [J].

ROWLANDS, MG ;

PARR, IB ;

MCCAGUE, R ;

JARMAN, M ;

GODDARD, PM .

BIOCHEMICAL PHARMACOLOGY, 1990, 40 (02) :283-289

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