GENOME ORGANIZATION IN PROKARYOTES

被引：12

作者：

CAMPBELL, AM ^{[1
]}

机构：

[1] STANFORD UNIV, DEPT BIOL SCI, STANFORD, CA 94305 USA

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 1993年 / 3卷 / 06期

关键词：

D O I：

10.1016/0959-437X(93)90002-7

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Most of the well-characterized prokaryotic genomes consist of double-stranded DNA organized as a single circular chromosome 0.6-10 Mb in length and one or more circular plasmid species of 2 kb-1.7 Mb. The past few years, however, have revealed some major variations in genome organization. In addition, a recent accumulation of data has shown that the location and orientation of the genes and repeated sequences (including prophages and transposons) on and among these elements is not always random. Some of the non-randomness is probably the result of unique historical events; in other cases it reflects selection for the optimization of function.

引用

页码：837 / 844

页数：8

共 56 条

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