A THEORETICAL-MODEL FOR THE USE OF FUNCTIONAL ANTAGONISM TO ESTIMATE DISSOCIATION-CONSTANTS FOR AGONISTS

被引：14

作者：

AMIDON, GL ^{[1
]}

BUCKNER, CK ^{[1
]}

机构：

[1] UNIV WISCONSIN,SCH PHARM,MADISON,WI 53706

来源：

JOURNAL OF PHARMACOLOGICAL METHODS | 1982年 / 7卷 / 02期

关键词：

D O I：

10.1016/0160-5402(82)90030-4

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：173 / 178

页数：6

共 15 条

[1]

AMIDON GL, 1981, J PHARMACOL EXP THER, V216, P352

[2]

ARIENS EJ, 1964, MOL PHARM, V1

[3] SOME QUANTITATIVE USES OF DRUG ANTAGONISTS [J].

ARUNLAKSHANA, O ;

SCHILD, HO .

BRITISH JOURNAL OF PHARMACOLOGY AND CHEMOTHERAPY, 1959, 14 (01) :48-58

[4] AFFINITY AND EFFICACY OF ONIUM SALTS ON FROG RECTUS ABDOMINIS [J].

BARLOW, RB ;

SCOTT, NC ;

STEPHENSON, RP .

BRITISH JOURNAL OF PHARMACOLOGY AND CHEMOTHERAPY, 1967, 31 (01) :188-+

[5] FUNCTIONAL ANTAGONISM AS A MEANS OF DETERMINING DISSOCIATION-CONSTANTS AND RELATIVE EFFICACIES OF SYMPATHOMIMETIC AMINES IN GUINEA-PIG ISOLATED ATRIA [J].

BROADLEY, KJ ;

NICHOLSON, CD .

BRITISH JOURNAL OF PHARMACOLOGY, 1979, 66 (03) :397-404

[6] STUDIES ON BETA-ADRENOCEPTORS MEDIATING CHANGES IN MECHANICAL EVENTS AND ADENOSINE-3',5'-MONOPHOSPHATE LEVELS - RAT ATRIA [J].

BUCKNER, CK ;

TORPHY, T ;

COSTA, DJ .

EUROPEAN JOURNAL OF PHARMACOLOGY, 1978, 47 (03) :259-271

[7]

BUCKNER CK, 1975, J PHARMACOL EXP THER, V194, P565

[8]

CLARK AJ, 1937, HDB EXPT PHARM, V4

[9] COMPARISON OF DISSOCIATION CONSTANTS AND OF RELATIVE EFFICACIES OF SELECTED AGONISTS ACTING ON PARASYMPATHETIC RECEPTORS [J].

FURCHGOTT, RF ;

BURSZTYN, P .

ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1967, 144 (A2) :882-+

[10]

FURCHGOTT RF, 1955, PHARMACOL REV, V7, P183

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