A NEW SYNTHESIS OF 2-SUBSTITUTED 6-ENDO-(METHYLTHIO)BICYCLO[2.2.1]HEPTANES - SYNTHESIS AND CRYSTAL AND MOLECULAR-STRUCTURE OF A CONFORMATIONALLY RESTRICTED METHIONINE ANALOG

被引：13

作者：

GLASS, RS

SABAHI, M

SINGH, WP

机构：

[1] Department of Chemistry, University of Arizona, Tucson

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1992年 / 57卷 / 09期

关键词：

D O I：

10.1021/jo00035a026

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new and advantageous synthesis of 2-endo-substituted-6-endo-(methylthio)bicyclo[2.2.1]heptanes, especially suitable for the preparation of such compounds with 2-endo-hydroxy and amino substituents, is presented. Also reported is the synthesis of the conformationally restricted methionine analogue (+/-)-2-endo-amino-6-endo-(methylthio)bicyclo[2.2.1]heptane-2-exo-carboxylic acid and its crystal and molecular structure determined by X-ray crystallographic techniques.

引用

页码：2683 / 2688

页数：6

共 43 条

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