HETEROCYCLIC VARIANTS OF THE 1,5-BENZODIAZEPINE SYSTEM .6. DERIVATIVES OF 2-METHYLTHIO-4-(PARA-R-PHENYL)-3H-1,5-BENZODIAZEPINES [1]

Ethyl 3-[H-3-1,5-benzodiazepin-2-yl]carbazates II were prepared in moderate yields from the title compounds and ethyl carbazate. The compounds II were easily transformed into 1H-s-triazolo[4,3-a][1,5]benzodiazepin-1-ones III via a one-step procedure. Reaction of triazolo-1,5-benzodiazepinones III with sodium hydride in methyl iodide gave a mixture of products from which were isolated two compounds IV and V. The structure of all products was confirmed by ir, H-1 nmr and mass spectrometry.