PHOTOREACTIONS OF FUROCOUMARINS WITH BIOMOLECULES

被引：25

作者：

CADET, J

VIGNY, P

MIDDEN, WR

机构：

[1] UNIV PARIS 06,PHYS & CHIM BIOMOLEC LAB,CNRS,UA 198,F-75231 PARIS 05,FRANCE

[2] BOWLING GREEN STATE UNIV,DEPT CHEM,CTR PHOTOCHEM SCI,BOWLING GREEN,OH 43403

来源：

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY | 1990年 / 6卷 / 1-2期

关键词：

furocoumarin photocycloadducts to DNA; furocoumarin-protein photoadducts; Furocoumarins; photocycloaddition products of furocoumarin to lipids; photodynamic effects;

D O I：

10.1016/1011-1344(90)85090-J

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Recent aspects of the photoreactions of linear and angular furocoumarins with DNA and related compounds, including [2 + 2] cycloaddition to pyrimidine bases, covalent attachment to the osidic moiety of adenine nucleosides and photodynamic effects, are surveyed. Reactions of photoexcited furocoumarins with proteins and unsaturated lipids and the possible biological roles of the resulting adducts are also presented and discussed. © 1990.

引用

页码：197 / 206

页数：10

共 59 条

[1] MOLECULAR DOSIMETRY OF 8-MOP+UVA-INDUCED DNA PHOTOADDUCTS IN SACCHAROMYCES-CEREVISIAE - CORRELATION OF LESIONS NUMBER WITH GENOTOXIC POTENTIAL [J].