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PREVENTION OF EXPERIMENTAL SUBARACHNOID HEMORRHAGE-INDUCED INTRACRANIAL ARTERIAL VASONECROSIS WITH PHOSPHODIESTERASE INHIBITOR PHTHALAZINOL (EG-626)

被引：22
作者：
ALKSNE, JF
BRANSON, PJ
机构：
[1] Division of Neurological Surgery (H-893), University of California Medical Center, San Diego University Hospital, San Diego, CA, 92103
来源：
STROKE | 1979年 / 10卷 / 06期
关键词：
D O I：
10.1161/01.STR.10.6.638
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Experiments in monkeys have demonstrated that the chronic vasospasm and arterial injury reaction produced by subarachnoid blood injection can be prevented by treatment with the phosphodiesterase inhibitor phthalazinol. This protective effect, which is present even when the drug treatment is initiated after the subarachnoid blood injection, is presumed to occur because of the platelet inhibiting effect of phthalazinol. © 1979 American Heart Association, Inc.
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页码：638 / 644
页数：7
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