GENOMIC ORGANIZATION AND DNA-SEQUENCE OF THE HUMAN CATECHOLAMINE-SULFATING PHENOL SULFOTRANSFERASE GENE (STM)

被引：26

作者：

DOOLEY, TP

PROBST, P

MUNROE, PB

MOLE, SE

LIU, Z

DOGGETT, NA

机构：

[1] UCL, RAYNE INST, DEPT PAEDIAT, LONDON WC1E 6JJ, ENGLAND

[2] LOS ALAMOS NATL LAB, DIV LIFE SCI, LOS ALAMOS, NM 87545 USA

[3] LOS ALAMOS NATL LAB, CTR HUMAN GENOME STUDIES, LOS ALAMOS, NM 87545 USA

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1994年 / 205卷 / 02期

关键词：

D O I：

10.1006/bbrc.1994.2810

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The human monoamine neurotransmitter-preferring phenol sulfotransferase (M-PST) plays an essential role in the sulfation of catecholamines, such as dopamine. The cDNA encoding M-PST has been reported, and we have recently identified cosmid clones from human chromosome 16p11.2 for this gene, STM. Plasmid subclones derived from the STM cosmid clones were subjected to dideoxynucleotide chain termination sequencing to determine the genomic organization and DNA sequence of STM. The gene encoding full-length STM is approximately 6.4 kb and contains 8 exons and 7 introns. (C) 1994 Academic Press, Inc.

引用

页码：1325 / 1332

页数：8

共 15 条

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