MATURATION OF RENAL ORGANIC ACID TRANSPORT - SUBSTRATE SIMULATION BY PENICILLIN

被引：69

作者：

HIRSCH, GH

HOOK, JB

机构：

[1] Department of Pharmacology, Michigan State University, East Lansing

来源：

SCIENCE | 1969年 / 165卷 / 3896期

关键词：

D O I：

10.1126/science.165.3896.909

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Renal p-aminohippurate transport in rabbits increased rapidly from birth to 4 weeks of age and then declined to that observed in adults. Penicillin administration to pregnant does or newborn rabbits stimulated the developing transport system, but did not increase the peak observed at 4 weeks. Therefore the continued presence of substrate (penicillin) during development significantly enhances the rate of maturation.

引用

页码：909 / &

共 16 条

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