Synthesis of potential anticancer agents. XXIII. 9-aminohypoxanthine and related compounds

被引:43
作者
Montgomery, John A. [1 ]
Temple, Carroll, Jr. [1 ]
机构
[1] So Res Inst, Kettering Meyer Lab, Birmingham, AL 35255 USA
关键词
D O I
10.1021/ja01502a037
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The reaction of 5-ainino-4-hydrazinopyrimidines with formic acid has been found to give 9-aminopurines rather than the isomeric 1,2-dihydropyrimido[5,4-e]-as-triazines. Some 1-alkyl-1,2-dihydropyrimido[5,4-e]-as-triazines were prepared from 4-(1-alkylhydrazino)-5-aminopyrimidines.
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页码:4592 / 4596
页数:5
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