PLANT ANTITUMOR AGENTS .4. AN APPROACH TOWARD SYNTHESIS OF CAMPTOTHECIN

被引:36
作者
KEPLER, JA
WANI, MC
MCNAULL, JN
WALL, ME
LEVINE, SG
机构
[1] Chemistry and Life Sciences Laboratory, Research Triangle Institute, Research Triangle Park, North Carolina, 27709
关键词
D O I
10.1021/jo01264a026
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The tricyclic compound 5 containing the A,B,C ring system of camptothecin (1) and suitable functionality for constructing the D and E rings has been synthesized. Some of the results obtained in attempts to convert 5 into the aldehyde 6 are described. © 1969, American Chemical Society. All rights reserved.
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页码:3853 / &
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