GAMMA-AMINOBUTYRIC-ACID INDUCES FEEDING-BEHAVIOR IN THE MARINE MOLLUSK, CLIONE-LIMACINA

被引：15

作者：

ARSHAVSKY, YL

GAMKRELIDZE, GN

ORLOVSKY, GN

PANCHIN, YV

POPOVA, LB

机构：

[1] KAROLINSKA INST,NOBEL INST NEUROPHYSIOL,BOX 60400,S-10401 STOCKHOLM 60,SWEDEN

[2] ACAD SCI USSR,INST PROBLEMS INFORMAT TRANSMISS,MOSCOW V-71,USSR

[3] MV LOMONOSOV STATE UNIV,AN BELOZERSKY LAB MOLEC BIOL & BIOORGAN CHEM,MOSCOW,USSR

来源：

NEUROREPORT | 1991年 / 2卷 / 04期

关键词：

MOLLUSK CLIONE-LIMACINA; GABA; FEEDING BEHAVIOR; ISOLATED NEURONS;

D O I：

10.1097/00001756-199104000-00002

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The effects of gamma-aminobutyric acid (GABA) on the behaviour of the marine pteropod mollusc Clione limacina were studied. In intact molluscs, injection of GABA evoked the consummatory stage of feeding behaviour, i.e. protracting the tentacles, opening the mouth, catching and swallowing prey, as well as some acceleration of locomotion. In the isolated CNS, GABA (10(-5)-10(-4) M) strongly activated the feeding rhythm generator, excited the cerebral motoneurons innervating tenacle muscles (TenMNs), and accelerated locomotor rhythm. A direct excitatory action of GABA (10(-8) M) upon TenMNs was demonstrated on isolated cells extracted from cerebral ganglia. It is concluded that GABA plays an important role in activation of various neuronal networks (organization of 'functional synergy') responsible for the consummatory stage of feeding behaviour.

引用

页码：169 / 172

页数：4

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