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FUTURE APPROACHES TO VACCINE DEVELOPMENT - SINGLE-DOSE VACCINES USING CONTROLLED-RELEASE DELIVERY SYSTEMS
被引：54
作者：
AGUADO, MT
机构：
来源：
关键词：
SINGLE-DOSE VACCINES;
CONTROLLED RELEASE;
MICROENCAPSULATION;
D O I：
10.1016/0264-410X(93)90241-O
中图分类号：
R392 [医学免疫学];
Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The development of single-dose vaccines, mainly those administered during childhood, which would effectively protect against certain diseases, would be a very important advance towards better immunization coverage and protection against the respective pathogens. Biodegradable polymeric microspheres which are 'programmed' to deliver the antigen when a boost of the immune response is required, may be a possible way of achieving this goal.
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页码：596 / 597
页数：2
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