UV-B RADIATION-INDUCED CATARACT IN THE ROYAL-COLLEGE OF SURGEONS RAT

被引：18

作者：

BREADSELL, RO ^{[1
]}

WEGENER, A ^{[1
]}

BREIPOHL, W ^{[1
]}

HIRST, LW ^{[1
]}

机构：

[1] UNIV BONN,INST EXPTL OPHTHALMOL,W-5300 BONN,GERMANY

来源：

OPHTHALMIC RESEARCH | 1994年 / 26卷

关键词：

CATARACT; UV-B RADIATION; RSC RAT; LENS FIBER CELL; RAT LENS;

D O I：

10.1159/000267522

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Cataractogenesis was studied in Royal College of Surgeon (RCS) rats which carry a recessive gene for retinal dystrophy. To examine the impact of this syndrome on cataractogenesis, the cortical lens damage in the UV-B radiation-induced cataract and in the hereditary cataract were compared in homozygous (affected) and heterozygous (unaffected) pink-eyed, tan-hooded RCS rats. The findings from this investigation suggest that the early changes in both the radiation-induced anterior subcapsular cataract and the hereditary posterior subcapsular cataract are at the level of the fibre cell membrane.

引用

页码：84 / 89

页数：6

共 21 条

[1] ULTRAVIOLET-LIGHT EXPOSURE AND RISK OF POSTERIOR SUBCAPSULAR CATARACTS [J].