ANTIULCER ACTION AND TOXICITY OF STYRAX-CAMPORUM AND CAESALPINIA-FERREA

被引：38

作者：

BACCHI, EM

SERTIE, JAA

VILLA, N

KATZ, H

机构：

[1] UNIV SAO PAULO, INST CIENCIAS BIOMED, DEPT FARMACOL, FARMACOL & TOXICOL PROD NAT LAB, BR-05508 SAO PAULO, BRAZIL

[2] UNIV SAO PAULO, INST CIENCIAS BIOMED, DEPT HISTOL & EMBRIOL, BR-05508 SAO PAULO, BRAZIL

[3] FAC OSWALDO CRUZ, SAO PAULO, BRAZIL

来源：

PLANTA MEDICA | 1995年 / 61卷 / 03期

关键词：

STYRAX CAMPORUM POHL; STYRACACEAE; CAESALPINIA FERREA MARTIUS; LEGUMINOSAE; ANTIULCER ACTION; TOXICITY;

D O I：

10.1055/s-2006-958056

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Oral administration of Styrax camporum Pohl and Caesalpinia ferrea Martius stem extracts, atropine, and cimetidine, during 15 days, decreased the ulceration size, gastric secretion volume, and increased collagen fibre number of chronic ulcer induced by acetic acid in rats. The pH increased and the concentration of hydrochloric acid decreased after administration of atropine and cimetidine. The ethyl acetate fraction, obtained by chromatography from Styrax camporum Pohl extracts, showed antiulcer activity. The subchronic toxicity was studied during 30 days, through weight variation, water and food consumption and spleen, lung, kidney and liver relative weights. No difference to the control-lot was observed.

引用

页码：204 / 207

页数：4

共 21 条

[1]

ALBELDA RM, 1973, REV ESP ENFERM APAR, V41, P771

[2] ANTIULCER ACTION OF STYRAX-CAMPORUM AND CAESALPINIA-FERREA IN RATS [J].

BACCHI, EM ;

SERTIE, JAA .

PLANTA MEDICA, 1994, 60 (02) :118-120

[3]

BACCHI EM, 1989, THESIS U SAO PAULO

[4]

Chan P.K., 1982, PRINCIPLES METHODS T

[5]

COIMBRA R, 1942, NOTAS FITOTERAPIA

[6]

Cruz GL, 1965, LIVRO VERDE PLANTAS, V2

[7]

CRUZ GL, 1965, LIVRO VERDE PLANTAS, V1

[8]

Giesbrecht A. M., 1985, ANAIS FARMACIE QUIMI, V25, P55

[9]

HUSEYIN A, 1980, PHYTOCHEMISTRY, V19, P2784

[10]

JENNEWEIN HM, 1980, ADV ULCER DISEASE

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